How is Abciximab dosed?
The recommended dosage of abciximab for adults is initially 250 micrograms per kilogram of body weight, injected 10 to 60 minutes before the percutaneous coronary intervention procedure. The maintenance dose is 0.125 micrograms per kilogram of body weight per minute (maximum of 10 micrograms per minute) administered intravenously for 12 hours. The dosage for children must be determined by a doctor. For patients with unstable angina undergoing percutaneous coronary intervention within 24 hours, the initial dose is 250 micrograms per kilogram of body weight, and the maintenance dose is 10 micrograms per minute administered intravenously for 18 to 24 hours, ending 1 hour after the procedure.
What is the dosage form of Abciximab?
Abciximab is available in intravenous dosage forms. The dosage forms for prevention of blood clots during percutaneous coronary intervention are as follows:
- Adults: Initial dose of 250 micrograms (mcg) per kilogram (kg) of body weight injected 10 to 60 minutes before the procedure. Maintenance dose of 0.125 mcg per kg of body weight per minute (maximum of 10 mcg per minute) administered intravenously for 12 hours.
- Children: Use and dose must be determined by a doctor. For patients with unstable angina undergoing percutaneous coronary intervention within 24 hours:
- Adults: Initial dose of 250 micrograms (mcg) per kilogram (kg) of body weight injected. Maintenance dose of 10 mcg per minute by intravenous route for 18 to 24 hours, ending 1 hour after the procedure.
- Children: Use and dose must be determined by a doctor. Please consult with your doctor or healthcare professional for the appropriate dosage and usage based on your specific medical condition and other factors.
What medications are contraindication with Abciximab?
Abciximab is contraindicated with certain medications including Aceclofenac, Acemetacin, Acenocoumarol, Alipogene Tiparvovec, Alteplase, Recombinant, Amtolmetin Guacil, Anagrelide, Apixaban, Ardeparin, Argatroban, Bemiparin, Betrixaban, Bivalirudin, Bromfenac, Bufexamac, Caplacizumab-yhdp, Celecoxib, Certoparin, Choline Salicylate, Cilostazol, Citalopram, Clonixin, Clopidogrel, Curcumin, Dabigatran Etexilate, Dalteparin, Danaparoid, Desirudin, Desvenlafaxine, Dexibuprofen, Dexketoprofen, Dextran, Diclofenac, Diflunisal, Dipyridamole, Dipyrone, Drotrecogin Alfa, Droxicam, Duloxetine, Edoxaban, Enoxaparin, Escitalopram, Etodolac, Etofenamate, Etoricoxib, Felbinac, Fenoprofen, Fepradinol, Feprazone, Floctafenine, Flufenamic Acid, Fluoxetine, Flurbiprofen, Fluvoxamine, Fondaparinux, Heparin, and Ibrutinib. Please consult with your doctor or healthcare professional for a complete list of contraindicated medications.
How is Abciximab administered?
Abciximab is administered by injection into a vein and is used to lessen the chance of heart attack in people undergoing percutaneous coronary intervention (PCI), a procedure to open blocked arteries of the heart. The initial dose for prevention of blood clots during PCI is 250 micrograms (mcg) per kilogram (kg) of body weight, injected 10 to 60 minutes before the procedure. The maintenance dose is 0.125 mcg per kg of body weight per minute (maximum of 10 mcg per minute) by intravenous route for 12 hours. For patients with unstable angina undergoing PCI within 24 hours, the initial dose is 250 mcg/kg, and the maintenance dose is 10 mcg per minute by intravenous route for 18 to 24 hours, ending 1 hour after the procedure. Doses for children must be determined by a doctor.
What are common precautions when taking Abciximab?
Common precautions when taking abciximab include informing your doctor about other medical conditions, medications, or allergies you have, as well as any recent bleeding episodes, strokes, falls, or major surgeries. This medicine may increase the risk of serious bleeding for certain individuals. It is important to follow your doctor's orders or the instructions on the label regarding dosing, timing, and frequency of the injections. Elderly patients may be more sensitive to the effects of abciximab and may experience bleeding problems. Breastfeeding mothers should consult their doctors before using this medication. The drug may cause side effects such as back pain, stomach issues, mood changes, and skin sensations. Report any unexpected effects to your healthcare professional.