Antithyroid Agent

How is Antithyroid Agent dosed?

For oral dosage forms (tablets):

  • For treatment of hyperthyroidism (overactive thyroid):
    • Adults and teenagers: Initially, 300 to 900 milligrams (mg) a day. Some people may need up to 1200 mg a day. This may be taken as a single dose or divided into two to four doses in a day. Later, the doctor may lower the dose to 50 to 600 mg a day.

For rectal dosage forms (enemas or suppositories):

  • For treatment of thyrotoxicosis (a thyroid emergency):
    • Adults and teenagers: 200 to 400 mg inserted into the rectum every four hours. The doctor may change the dose as needed.
    • Children 6 to 10 years of age: 50 to 150 mg inserted into the rectum a day. This dose may be used as a single dose or divided into two to four doses in a day. The doctor may change the dose as needed.
    • Children 10 years of age and older: 50 to 300 mg inserted into the rectum a day. This dose may be used as a single dose or divided into two to four doses in a day. The doctor may change the dose as needed.
    • Newborn infants: Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg per kg (4.5 mg per pound) of body weight inserted into the rectum. This is usually divided into more than one dose a day. The doctor may change the dose as needed.

What is the dosage form of Antithyroid Agent?

For oral dosage form (tablets):

  • For treatment of hyperthyroidism (overactive thyroid):
    • Adults and teenagers: Initially, 300 to 900 milligrams (mg) a day. Some people may need up to 1200 mg a day. This may be taken as a single dose or divided into two to four doses in a day. Later, the doctor may lower the dose to 50 to 600 mg a day.

For rectal dosage forms (enemas or suppositories):

  • For treatment of thyrotoxicosis (a thyroid emergency):
    • Adults and teenagers: 200 to 400 mg inserted into the rectum every four hours. The doctor may change the dose as needed.
    • Children 6 to 10 years of age: 50 to 150 mg inserted into the rectum a day. This dose may be used as a single dose or divided into two to four doses in a day. The doctor may change the dose as needed.
    • Children 10 years of age and older: 50 to 300 mg inserted into the rectum a day. This dose may be used as a single dose or divided into two to four doses in a day. The doctor may change the dose as needed.
    • Newborn infants: Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg per kg (4.5 mg per pound) of body weight inserted into the rectum. This is usually divided into more than one dose a day. The doctor may change the dose as needed.

For rectal dosage form (suppositories):

  • For treatment of thyrotoxicosis (a thyroid emergency):
    • Adults and teenagers: 15 to 20 mg inserted into the rectum every four hours. The doctor may change the dose as needed.
    • Children: The dose is based

How is Antithyroid Agent administered?

Antithyroid agents are administered through tablets and suppositories. For rectal dosage forms, the medication is inserted into the rectum, while for oral dosage forms, it is taken by mouth. The specific administration method and dosage depend on the individual's age, medical condition, and the particular antithyroid agent being used (e.g., methimazole or propylthiouracil). Always follow your doctor's instructions and the dosage information provided with the medication.

What are common precautions when taking Antithyroid Agent?

It is important to follow the prescribed dosage and frequency of administration as directed by your healthcare professional. If you experience any unusual or severe side effects, contact your doctor immediately.