Bedaquiline Oral Route

How is Bedaquiline Oral Route dosed?

The usual dose for the treatment of multidrug-resistant tuberculosis (MDR-TB) is 400 mg (two 200 mg tablets or one 100 mg tablet) taken once a week, administered under direct observation. The tablets should be swallowed whole with food.

What is the dosage form of Bedaquiline Oral Route?

The available dosage form of Bedaquiline Oral Route is tablets.

How is Bedaquiline Oral Route administered?

Bedaquiline Oral Route should be taken with food. The 100-mg tablet should be swallowed whole. If the patient can swallow the 20-mg tablet whole, it can also be taken with food. If the tablet cannot be swallowed whole, it can be crushed and mixed with soft food, such as yogurt, applesauce, mashed banana, or porridge, and then swallowed immediately. The mixture should be consumed right away, and no medicine should be left in the container.

What are common precautions when taking Bedaquiline Oral Route?

Common precautions when taking Bedaquiline Oral Route include:

  1. Kidney disease: Use with caution in patients with severe kidney disease.
  2. Liver disease: Use with caution as it may worsen the condition.
  3. Proper use: Take the medicine exactly as directed by your doctor.
  4. Directly observed therapy (DOT): Bedaquiline must always be taken with at least three other medicines for TB.
  5. Medication Guide: Read and follow the instructions in the provided Medication Guide carefully.
  6. Food intake: It is best to take this medicine with food.
  7. Tablet form: Swallow the 100-mg tablet whole with water, avoid crushing, breaking, or chewing it. Take it with food. For the 20-mg tablet, follow the instructions provided by your doctor.
  8. Allergies: Inform your doctor if you have any allergies.
  9. Pediatric use: Bedaquiline has been found to be safe and effective in children aged 5 and older and weighing at least 15 kg.
  10. Geriatric use: No specific problems have been identified in elderly patients.
  11. Breastfeeding: Consult your doctor before using this medicine if you are breastfeeding.