How is Carbidopa and Levodopa dosed?
The dosage for adults usually does not exceed 2000 milligrams of levodopa (one cassette) administered over a 16-hour period. Pediatric dosing is determined by the doctor. It's essential to follow the prescribed dosage and consult with a healthcare professional for any questions or concerns regarding dosing.
What is the dosage form of Carbidopa and Levodopa?
Carbidopa and levodopa is available in the form of an enteral suspension, which is administered through a tube inserted into the stomach or small intestine, bypassing the stomach and intestinal digestive processes.
What medications are contraindication with Carbidopa and Levodopa?
Carbidopa and levodopa should not be taken with the following medications:
- Amisulpride
- Bupropion
- Haloperidol
- Isoniazid
- Macimorelin
- Metoclopramide
- Olanzapine
- Sapropterin
- Droxidopa
- Fosphenytoin
- Indinavir
- Iron
- Kava
- Phenylalanine
- Phenytoin
- Spiramycin
- Tyrosine Please consult with your doctor before taking any medications, as they may need to adjust the dose or frequency of these medications to ensure your safety.
How is Carbidopa and Levodopa administered?
Carbidopa and levodopa is administered through a PEG-J tube, which is a small hole made in the stomach to deliver the medication directly into the intestines. The dose is programmed into a pump by a healthcare professional and should only be changed by a doctor.
What are common precautions when taking Carbidopa and Levodopa?
Common precautions when taking carbidopa and levodopa include:
- Allergies: Inform your doctor if you're allergic to carbidopa, levodopa, or any other medications.
- Pediatric Use: The safety and efficacy of carbidopa and levodopa in pediatric populations have not been established.
- Geriatric Use: Elderly patients may be more sensitive to the side effects of this medicine, such as low blood pressure, fainting, or confusion.
- Stomach Surgery or Problems: Inform your doctor if you have had stomach surgery or problems with your stomach, as this medicine requires a special procedure to place a PEG-J tube.
- High-Protein Diets: Avoid high-protein diets, as protein may interfere with the body's response to carbidopa and levodopa. Normal amounts of protein should be spaced evenly throughout the day, or taken as directed by your doctor.
- Night-Time Dose: Keep a supply of carbidopa-levodopa immediate-release tablets for your prescribed night-time dose after receiving your Duopa dose.
Always follow your doctor's instructions and consult them before making any changes to your dosage or treatment.