Dalfampridine

How is Dalfampridine dosed?

The recommended oral dosage for dalfampridine (Ampyra) is 10 milligrams (mg) taken twice a day, with at least a 12-hour interval between doses. The maximum daily dose should not exceed 2 tablets (20 mg). Dosing for children should be determined by a doctor.

What is the dosage form of Dalfampridine?

Dalfampridine is available in extended-release tablets for oral administration.

What medications are contraindication with Dalfampridine?

Dalfampridine should not be taken with other aminopyridine medicines such as compounded 4-AP or fampridine, as this may increase the risk of serious side effects. Caution should be exercised when administering dalfampridine to elderly patients, as they are more prone to seizures and age-related kidney problems. Always consult with your healthcare professional before taking any medication, including over-the-counter products and herbal or vitamin supplements, while using dalfampridine.

How is Dalfampridine administered?

Dalfampridine should be taken exactly as directed by a doctor and never crushed, broken, chewed, or dissolved. The tablet should be swallowed whole. It can be taken with or without food. Always consult with a healthcare professional before starting any medication or altering the dosage.

What are common precautions when taking Dalfampridine?

Common precautions when taking dalfampridine orally include:

  1. Checking with your doctor right away if you have seizures while taking this medicine.
  2. Avoiding taking dalfampridine with other aminopyridine medicines, as this may increase the chance for more serious side effects.
  3. Being aware that the medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Notify your doctor if you experience a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.
  4. Refraining from driving or engaging in any activities that could be dangerous when you feel dizzy, lightheaded, or experience a constant movement of self or surroundings, as the medicine may cause these effects.
  5. Consulting your doctor before taking any other medicines, including prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements, as they may interact with dalfampridine. It is also important to inform your doctor about any allergies you have, including allergies to foods, dyes, preservatives, or animals, and any geriatric, pediatric, or breastfeeding concerns. Dosing and use of dalfampridine should be directed by your doctor and followed closely based on your specific medical condition and response to treatment.