How is Enasidenib Oral Route dosed?
Enasidenib (Oral Route) is typically dosed based on the individual patient's condition, medical history, and response to the treatment. The drug is prescribed by a doctor and taken under medical supervision. The dosage form is a tablet. For specific details on dosing, it is best to consult with a healthcare professional, as they have access to the most up-to-date information regarding the patient's unique medical situation.
What is the dosage form of Enasidenib Oral Route?
Enasidenib is available in tablet form for oral use.
What medications are contraindication with Enasidenib Oral Route?
Enasidenib oral route has several contraindications with other medications. Here are some notable contraindications:
- Atorvastatin: Concomitant use of enasidenib and atorvastatin may increase the risk of myopathy and rhabdomyolysis.
- Bosentan: Coadministration of enasidenib and bosentan may result in increased bosentan concentrations and associated toxicity.
- Digoxin: Enasidenib may increase digoxin concentrations, increasing the risk of digoxin toxicity.
- Elagolix: The concomitant use of enasidenib and elagolix may result in decreased efficacy of elagolix.
- Glyburide: Enasidenib may increase glyburide concentrations, increasing the risk of hypoglycemia.
- Grazoprevir: Coadministration of enasidenib and grazoprevir may increase the risk of diarrhea, nausea, and vomiting.
- Irinotecan: Enasidenib may decrease irinotecan concentrations, reducing its efficacy.
- Letermovir: Coadministration of enasidenib and letermovir may increase the risk of nephrotoxicity.
- Methotrexate: Enasidenib may decrease methotrexate concentrations, reducing its efficacy.
- Ozanimod: Coadministration of enasidenib and ozanimod may increase the risk of infection. It is essential to consult with a healthcare professional before combining enasidenib with any other medications, as interactions may occur.
How is Enasidenib Oral Route administered?
Enasidenib oral route is administered as a tablet that should be swallowed whole with 1 cup (8 ounces) of water. It is important not to crush, break, or chew the tablet. Always follow your doctor's instructions and read the Medication Guide carefully before using the medication.
What are common precautions when taking Enasidenib Oral Route?
Common precautions when taking enasidenib oral route include informing your doctor about any allergies you may have, including allergies to foods, dyes, preservatives, or animals. Additionally, you should notify your healthcare professional if you have had any unusual or allergic reactions to this medicine or any other medicines in the past. Enasidenib has not been studied in the pediatric population, so its safety and efficacy have not been established for children. There is limited information available on its use during breastfeeding, so you should weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Lastly, you should be cautious about using this medicine with certain foods, alcohol, or tobacco, as interactions may occur. It is important to discuss these precautions with your healthcare professional before using enasidenib.