Entrectinib

How is Entrectinib dosed?

The dosage of entrectinib is determined by the individual patient's prescription provided by their healthcare professional. The dose and frequency of administration may vary based on the patient's specific condition, body weight, and response to treatment. It is important to follow the dosing instructions carefully and not take more or less than prescribed. If you have any questions about your dosage, consult your doctor or pharmacist for guidance.

What is the dosage form of Entrectinib?

Entrectinib is available in oral capsule form.

What medications are contraindication with Entrectinib?

Entrectinib should not be taken with the following medications:

  1. Bepridil
  2. Cisapride
  3. Dronedarone
  4. Fluconazole
  5. Ketoconazole
  6. Levoketoconazole
  7. Mesoridazine
  8. Pimozide
  9. Piperaquine
  10. Posaconazole
  11. Saquinavir
  12. Sparfloxacin
  13. Terfenadine
  14. Thioridazine
  15. Ziprasidone Consult your healthcare professional before combining entrectinib with any other medications to ensure there are no potential interactions or necessary precautions.

How is Entrectinib administered?

Entrectinib should be taken as directed by a doctor. The capsule should be swallowed whole and not opened, crushed, chewed, or dissolved. It can be taken with or without food.

What are common precautions when taking Entrectinib?

When taking entrectinib, it is important to take the following precautions:

  1. Allergies: Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
  2. Pediatric: The safety and efficacy of entrectinib for treating ROS1-positive NSCLC in children have not been established.
  3. Heart rhythm problems: Consult your doctor if you have a history of heart rhythm problems, QT prolongation, or slow heartbeat, as this medicine may exacerbate these conditions.
  4. Hyperuricemia: If you have high uric acid in the blood, use entrectinib with caution, as it may worsen your condition.
  5. Liver disease: Patients with liver disease should use entrectinib with caution, as it may worsen their condition.
  6. Proper use: Follow your doctor's directions carefully when using this medicine. Do not take more, take it more often, or take it for a longer time than prescribed.
  7. Side effects: Be aware of common side effects such as change or loss of taste, diarrhea, and difficulty having a bowel movement. Report any other effects to your healthcare professional. Work closely with your doctor during treatment and read the patient information leaflet carefully before taking the medicine.