Erdafitinib (Oral Route)

How is Erdafitinib (Oral Route) dosed?

The recommended initial dosage of erdafitinib for bladder cancer is 8 milligrams (mg) once a day. The dosage may be increased to 9 mg once a day based on the patient's phosphate levels, as assessed by the doctor at 14 to 21 days.

What is the dosage form of Erdafitinib (Oral Route)?

Erdafitinib is available in tablet form under the brand name Balversa. It is used to treat urothelial carcinoma (bladder cancer) that has spread or cannot be removed by surgery in patients with an abnormal "FGFR" gene in their cancer and who have tried at least one other chemotherapy medicine containing platinum that did not work well.

What medications are contraindication with Erdafitinib (Oral Route)?

Erdafitinib oral route is contraindicated with the following medications:

  1. Rifabutin
  2. Rifampin
  3. Sevelamer Carbonate
  4. Sevelamer Hydrochloride
  5. Sirolimus
  6. Sodium Bicarbonate
  7. Sodium Ferric Gluconate Complex
  8. Sodium Phosphate
  9. Sodium Phosphate, Dibasic
  10. Sodium Phosphate, Monobasic
  11. St John's Wort
  12. Sucroferric Oxyhydroxide
  13. Tacrolimus
  14. Temsirolimus It's important to inform your doctor about all medications and supplements you are taking, including any contraindicated medications, to ensure safe usage.

How is Erdafitinib (Oral Route) administered?

Erdafitinib oral route is administered as a tablet. The initial dose for adults is 8 milligrams (mg) (two 4 mg tablets) taken once a day. The dose may be increased to 9 mg (three 3 mg tablets) once a day based on phosphate levels, typically after 14 to 21 days of treatment. Children's dosages are determined by their doctor. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep it out of reach of children and do not keep outdated or unneeded medicine. Consult your healthcare professional for proper disposal of unused medicine.

What are common precautions when taking Erdafitinib (Oral Route)?

Common precautions when taking erdafitinib oral route include:

  1. Allergies: Inform your doctor if you have had any allergic reactions or sensitivities to this medicine or other medications.
  2. Eye or vision problems: Use erdafitinib with caution if you have pre-existing eye or vision issues, as it may worsen these conditions.
  3. Hyperphosphatemia (high potassium levels in the blood): Consult your doctor if you have high potassium levels before using this medication, as it may exacerbate the condition.
  4. Proper use: Follow your doctor's instructions carefully when taking erdafitinib, and be aware of potential side effects.
  5. Dosing: Adhere to your doctor's recommendations for dosage and frequency of intake. Do not take more or less than prescribed.