Etravirine

How is Etravirine dosed?

For the treatment of HIV infection in adults, the recommended dose of Etravirine is 200 milligrams (mg) taken orally twice a day. For children weighing 30 kilograms (kg) or more, the recommended dose is also 200 mg taken orally twice a day. The dose for children weighing less than 30 kg should be determined by a doctor. It is important to follow the dosage instructions provided by your doctor or the label and not to change the dose without consulting a healthcare professional.

What is the dosage form of Etravirine?

Etravirine is available in tablet form for oral administration.

What medications are contraindication with Etravirine?

Etravirine should not be used with the following medications:

  1. Dasabuvir
  2. Maraviroc
  3. Mavacamten Using etravirine with these medications may require adjustments in dosage or may not be recommended at all. It is important to consult with your healthcare professional before using etravirine in combination with any other medications. Please consult your doctor for specific advice regarding contraindications and interactions with etravirine.

How is Etravirine administered?

Etravirine should be taken orally with a liquid, preferably water. The tablet should be swallowed whole and not chewed. If swallowing the tablet whole is difficult, it can be dissolved in a small amount of water (1 teaspoon) to form a milky mixture. Additional water, orange juice, or milk can be added to make it easier to consume. Grapefruit juice, warm or carbonated drinks should not be used. The entire mixture should be drunk right away, and then the glass should be refilled with water, orange juice, or milk and consumed to ensure no medicine is left in the glass. It is important to follow the dosing instructions provided by a doctor and take the medicine exactly as directed, not taking more or more often than prescribed.

What are common precautions when taking Etravirine?

When taking Etravirine orally, it is important to:

  1. Follow the instructions provided by your doctor: Take the medicine exactly as directed, not more often, and for the duration prescribed.
  2. Take it with food: It is best to take Etravirine after a meal.
  3. Swallow the tablet whole: Do not chew or crush the tablet; swallow it with a liquid (e.g., water).
  4. Dissolve the tablet in water if necessary: If you or your child cannot swallow the tablet whole, dissolve it in a glass with a small amount of water (1 teaspoon), stir until milky, add more water, orange juice, or milk, and drink the entire mixture right away.
  5. Avoid certain drinks: Do not use grapefruit juice, warm or carbonated drinks while taking this medicine.
  6. Finish the entire dose: After dissolving the tablet, refill the glass with water, orange juice, or milk, and drink it to ensure no medicine is left in the glass.
  7. Considerations for children: Etravirine is not recommended for children younger than 2 years of age due to a lack of safety and efficacy data.
  8. Considerations for elderly patients: Elderly patients may require a dose adjustment, as they are more likely to have age-related liver, kidney, or heart problems.
  9. Breastfeeding: Consult your doctor before taking Etravirine while breastfeeding, as there is limited information on its safety for infants.
  10. Drug interactions: Inform your doctor about all other medications you are taking, as Etravirine may interact with other drugs, causing side effects or reducing effectiveness. Remember to consult your doctor or pharmacist if you have any questions or concerns about taking Etravirine.