How is Glipizide and Metformin Oral Route dosed?
For adults with type 2 diabetes starting treatment, the recommended dose is 2.5 milligrams (mg) of glipizide and 250 milligrams (mg) of metformin once a day with a meal. The dose may be gradually increased every two weeks by your doctor until blood sugar is controlled. For second-line therapy, the dose can be 2.5 mg of glipizide and 500 mg of metformin or 5 mg of glipizide and 500 mg of metformin, taken twice a day with morning and evening meals. Children's dosages should be determined by a doctor. It is important to follow your doctor's instructions and adjust the dose as needed based on blood sugar control and potential side effects. Always consult your healthcare provider for dosing information specific to your situation.
What is the dosage form of Glipizide and Metformin Oral Route?
Tablets
What medications are contraindication with Glipizide and Metformin Oral Route?
Medications that may interact with glipizide and metformin and are contraindicated include ACE inhibitors, angiotensin II receptor blockers, beta blockers, diuretics, insulin, isoniazid, oral hypoglycemic medications, salicylates, sulfonylureas, and thiazides. It's essential to consult with your doctor or pharmacist before combining glipizide and metformin with any other medications, as they can provide specific guidance based on your medical history and current medications.
How is Glipizide and Metformin Oral Route administered?
Glipizide and metformin oral route is administered as tablets. For first-time treatment of type 2 diabetes, the recommended adult dose is 2.5 milligrams (mg) of glipizide and 250 milligrams (mg) of metformin once a day with a meal. The dose may be increased gradually every two weeks until blood sugar is controlled. Children's doses must be determined by a doctor. When used as second-line therapy, the recommended dose is 2.5 mg of glipizide and 500 mg of metformin or 5 mg of glipizide and 500 mg of metformin, taken orally, two times a day with the morning and evening meals. The starting dose should not exceed the daily dose of glipizide or metformin already being taken. Children's doses must also be determined by a doctor.
What are common precautions when taking Glipizide and Metformin Oral Route?
Common precautions when taking glipizide and metformin oral route include:
- Taking the medicine with meals to help reduce gastrointestinal side effects.
- Following the dosing instructions provided by your doctor or the label, as the dose may vary depending on medical conditions, age, and individual response to the medication.
- Monitoring blood sugar levels regularly, as glipizide and metformin can cause low or high blood sugar.
- Notifying your doctor if you experience any unusual symptoms, such as sudden weight loss, fatigue, or increased thirst and hunger.
- Avoiding the use of alcohol, as it can increase the risk of lactic acidosis.
- Informing your doctor of any other medical conditions, including kidney or liver disease, heart or blood vessel disorders, or surgery, as these may affect the use of glipizide and metformin.
- Not starting this medicine in adults over 80 years of age unless kidney function is not reduced.
- Consulting your doctor before taking this medication while breastfeeding, as there is limited information on its safety for infants.
- Being cautious when using other medications or substances, as interactions may occur with ethanol or other medical problems. Please consult with your healthcare provider for personalized advice on using glipizide and metformin orally.