Lenvatinib oral route

How is Lenvatinib oral route dosed?

For the oral route of lenvatinib, the dosage is as follows:

• For the treatment of advanced kidney cancer (used with everolimus):

  • Adults: 18 milligrams (mg) once a day. Your doctor may adjust your dose as needed.
  • Children: Use and dose must be determined by your doctor.

• For the treatment of advanced kidney cancer (used with pembrolizumab):

  • Adults: 14 milligrams (mg) plus pembrolizumab injection given by a healthcare provider every 3 weeks.

• For the treatment of hepatocellular carcinoma:

  • Recommended dose: 18 milligrams (mg) once a day.

Always follow your doctor's orders or the directions on the label. The dose may be adjusted as needed.

What is the dosage form of Lenvatinib oral route?

Lenvatinib is available in the following dosage forms for oral route: capsules.

How is Lenvatinib oral route administered?

Lenvatinib is administered orally, either by swallowing the capsule whole or by dissolving it in a small container or oral syringe with a liquid (such as water or apple juice). If you cannot swallow the capsule whole, you may place the required number of capsules (up to 5) into a small container or oral syringe and add 3 milliliters of liquid. Wait 10 minutes for the capsule shell to dissolve, then stir or shake the mixture for 3 minutes until the capsules are fully dissolved. It is important to follow your doctor's instructions and read the patient information insert carefully before using this medication.

What are common precautions when taking Lenvatinib oral route?

Common precautions when taking lenvatinib oral route include:

1. Informing your doctor about any allergies or unusual reactions to medications, foods, dyes, preservatives, or animals.
2. Being cautious if you have a dental problem, are taking medicine to treat bone problems (e.g., bisphosphonates, denosumab), or are undergoing invasive dental procedures, as lenvatinib may cause slow wound healing and serious jaw bone problems (osteonecrosis). You may need to stop using the medicine for at least 1 week before dental work or at least 2 weeks after major surgery.
3. Reporting any heavy jaw feeling, loosening of a tooth, pain, swelling, or numbness in the mouth or jaw to your doctor right away.
4. Consulting your doctor before using this medicine if you plan to have children, as some individuals who use lenvatinib have experienced infertility.
5. Avoiding the use of other medicines, including prescription or nonprescription (over-the-counter) medicines and herbal or vitamin supplements, without discussing them with your doctor.
6. Informing your doctor about any breastfeeding plans, as adequate studies have not been conducted to determine the risk to infants.

These precautions are essential to ensure the safe and effective use of lenvatinib oral route.