Lorlatinib

How is Lorlatinib dosed?

The typical dose for treating non-small cell lung cancer in adults is 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed and tolerated.

What is the dosage form of Lorlatinib?

Lorlatinib is available in tablet form.

What medications are contraindication with Lorlatinib?

Lorlatinib should not be used with the following medications unless specifically advised by your doctor:

  1. Carbamazepine
  2. Enzalutamide
  3. Fosphenytoin
  4. Ivosidenib
  5. Lumacaftor
  6. Mavacamten
  7. Mitotane
  8. Phenytoin
  9. Rifampin
  10. St. John's Wort Always consult your healthcare professional before combining any medications.

How is Lorlatinib administered?

Lorlatinib should be taken with or without food. The tablet should be swallowed whole, without chewing, crushing, or splitting it. The dosage, number of doses per day, time between doses, and length of treatment depend on the medical condition being treated and the individual patient's needs, as determined by a doctor.