How is Methotrexate oral route dosed?
Methotrexate oral route is dosed based on the individual's body size and medical condition. It is used to treat various conditions, including acute lymphoblastic leukemia (ALL), non-Hodgkin lymphoma, rheumatoid arthritis, psoriasis, and polyarticular juvenile idiopathic arthritis (pJIA). The dosage forms available are solution and tablet. The dosage must be determined by a doctor and may vary for different age groups and medical conditions. It is important to follow the doctor's instructions and adhere to the prescribed schedule.
What is the dosage form of Methotrexate oral route?
The dosage forms of methotrexate oral route include solution and tablet.
What medications are contraindication with Methotrexate oral route?
The following medications are contraindicated or should be used with caution with methotrexate oral route:
- Cola: Drinking cola or consuming foods containing caffeine while using methotrexate may reduce its effectiveness.
- Other Medical Problems: Methotrexate should not be used in patients with anemia, leukopenia (low white blood cells), severe liver disease, thrombocytopenia (low platelet blood level), or a weak immune system.
- Alcohol abuse: Patients with a history of alcohol abuse should avoid using methotrexate.
- Ascites (extra fluid in the stomach area) or pleural effusion (extra fluid in the lung): Methotrexate use should be approached with caution in patients with these conditions due to the potential for increased side effects.
- Kidney disease: Patients with kidney disease may require dosage adjustments or close monitoring while using methotrexate.
- Diabetes: Patients with diabetes may need to monitor their blood sugar levels more closely while using methotrexate, as it can affect glucose metabolism.
- Obesity: Overweight patients may be at a higher risk of developing side effects from methotrexate, such as increased risk of elevated liver enzymes or pancreatitis. It is important to discuss any concerns with your healthcare provider. Always consult your doctor before using any medications, including over-the-counter drugs, supplements, or herbal products, while using methotrexate, as some of these may interact with the medication and affect its efficacy or cause adverse side effects.
How is Methotrexate oral route administered?
Methotrexate oral route can be administered as a solution or a tablet. The specific administration method, dosage, and frequency depend on the medical condition being treated and the individual patient's circumstances. It is important to follow the doctor's prescription and instructions when using this medication.
What are common precautions when taking Methotrexate oral route?
When taking methotrexate orally, common precautions include:
- Avoiding people with infections: As methotrexate can lower the number of white blood cells, which increases the risk of infections, it is recommended to avoid people with infections.
- Monitoring for signs of infection: If you experience fever, chills, cough, hoarseness, lower back or side pain, or painful or difficult urination, consult your doctor immediately.
- Precautions for bleeding: Be cautious if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.
- Dental care: Be careful while using a regular toothbrush, dental floss, or toothpick. Consult with your medical doctor, dentist, or nurse for alternative ways to clean your teeth and gums. It is advisable to check with your medical doctor before getting any dental work done.
- Following dosage instructions: Take the medicine only as directed by your doctor. Do not use more of it, do it more often, or use it for a longer time than prescribed.
- Informing your doctor about other medical conditions: Let your doctor know about any other medical problems you have, especially alcohol abuse, anemia, leukopenia, liver disease, severe, thrombocytopenia, weak immune system, ascites, kidney disease, pleural effusion, diabetes, obesity, stomach or bowel problems, or infections.