How is Mifepristone Oral Route dosed?
For termination of pregnancy (70 days or less), the adult dose is 200 milligrams (mg) as a single dose on Day 1, followed 2 days later by 800 micrograms (mcg) (four-200 mcg tablets) of misoprostol as a single dose placed in the cheeks. The dosing should be followed as directed by your doctor. Children's use of mifepristone is not recommended.
What is the dosage form of Mifepristone Oral Route?
The oral route dosage forms of mifepristone include tablets.
What medications are contraindication with Mifepristone Oral Route?
Mifepristone is contraindicated in patients with a known hypersensitivity to mifepristone or any of its components. It is also contraindicated in patients with confirmed or suspected pregnancy beyond 70 days of gestation, ectopic pregnancy, chronic adrenal failure, inherited porphyria, hemorrhagic disorders or concurrent anticoagulant therapy, and concurrent long-term corticosteroid therapy.
How is Mifepristone Oral Route administered?
Mifepristone oral route is administered as a tablet, and it should be swallowed whole, not broken, crushed, or chewed. It is typically taken with a meal. The dosage and frequency of administration depend on the medical condition being treated and the individual patient's needs. For termination of pregnancy (70 days or less), the dosage is 200 mg as a single dose on Day 1, followed by 800 mcg (four 200 mcg tablets) of misoprostol two days later. It is important to follow the instructions provided by your doctor, as the administration process may vary based on individual circumstances.
What are common precautions when taking Mifepristone Oral Route?
Common precautions when taking mifepristone oral route include:
- Using the medicine under medical supervision: Mifepristone should be administered by a healthcare professional. It is not to be taken at home.
- Following a specific treatment regimen: The treatment requires three visits to your doctor. You will be given mifepristone at the first visit, misoprostol at the second visit, and a check-up to confirm the end of pregnancy at the third visit.
- Reporting side effects: Contact your doctor if you experience any side effects or have concerns about bleeding or cramping after taking the medication.
- Informing your doctor of certain medical conditions: Certain health conditions such as undiagnosed lower abdominal mass, porphyria, adrenal problems, autoimmune disorders, diabetes, heart failure, heart or blood vessel disease, heart rhythm problems, hypertension, lung disease, anemia, severe, inability of blood to clot properly, poor blood circulation, hypokalemia (low potassium in the blood), kidney disease, or liver disease may require caution or special consideration when taking mifepristone.
- Informing your doctor of other medications: Let your doctor know if you are taking any other medications, as some medications may interact with mifepristone or affect its effectiveness. It is essential to follow the instructions provided by your doctor and read the Medication Guide carefully before using mifepristone.