How is Mitapivat dosed?
The recommended oral dosage for mitapivat is as follows:
- For hemolytic anemia in patients with pyruvate kinase (PK) deficiency, the initial adult dose is 5 milligrams (mg) taken two times a day. The dose may be adjusted by your doctor, but typically does not exceed 50 mg taken two times a day. The dosing instructions for children should be determined by the doctor. It is important to follow your doctor's orders or the instructions on the label and not to change the dose unless advised by your doctor.
What is the dosage form of Mitapivat?
Mitapivat is available in tablet form.
What medications are contraindication with Mitapivat?
Mitapivat (Oral Route) may interact with the following medications:
- Posaconazole
- Primidone
- Rifabutin
- Rifampin
- Ritonavir
- Saquinavir
- Segesterone
- Sirolimus
- St. John's Wort
- Telaprevir
- Telithromycin
- Temsirolimus
- Ulipristal
- Verapamil
- Voriconazole
- Warfarin Consult with your doctor before using any of these medications together with Mitapivat (Oral Route).
How is Mitapivat administered?
Mitapivat oral route is administered by swallowing the tablets whole, without splitting, crushing, chewing, or dissolving them. The dosage and frequency of administration should be determined by a healthcare professional and followed as prescribed.
What are common precautions when taking Mitapivat?
Common precautions when taking mitapivat oral route include informing your doctor of any allergies, other types of allergies, such as to foods, dyes, preservatives, or animals, and any unusual or allergic reactions to medicines. It is also important to let your healthcare professional know if you have any other medical conditions or are taking any other medications, as drug interactions may occur. If you are breastfeeding, consult your doctor before taking this medication, as potential risks and benefits should be weighed. If you experience any side effects, consult your healthcare professional for medical advice.