Naloxone Nasal Spray

How is Naloxone Nasal Spray dosed?

For the nasal route of naloxone, the typical dose for an opioid overdose is one spray per nostril. If the patient does not respond or shows signs of continued respiratory depression, an additional dose can be given every 2 to 3 minutes, up to a total of four doses. However, it is important to seek emergency medical assistance immediately after administering the first dose, as naloxone is not a substitute for emergency medical care. Consult with your doctor and follow the specific dosing instructions provided for your situation.

What is the dosage form of Naloxone Nasal Spray?

The dosage form of naloxone nasal spray is a spray. The brand names for this medication include Kloxxadoé—‚ spray and Narcan spray. The dosage instructions differ slightly between the two products, but for opioid overdose, the general guidance is to administer the first dose and monitor the patient's response. If necessary, additional doses can be given every 2 to 3 minutes until the patient responds or emergency medical assistance becomes available.

What medications are contraindication with Naloxone Nasal Spray?

Naloxone nasal spray may interact with other medications, and some medications may require adjustments in dosage or may interact with naloxone. It is important to consult with a healthcare professional for advice on potential drug interactions and contraindications before using naloxone nasal spray.

How is Naloxone Nasal Spray administered?

To administer naloxone nasal spray:

  1. Remove the nasal spray from the box and peel back the tab with the circle to open it.
  2. Lay the patient on their back, supporting their neck with your hand and allowing their head to tilt back.
  3. Gently insert the tip of the nozzle into one nostril of the patient, with your fingers on either side of the nozzle against the bottom of the patient's nose.
  4. Press the plunger firmly to give the dose.
  5. Remove the nasal spray from the patient's nostril after giving the dose.
  6. Move the patient to their side (recovery position) and seek emergency medical help right away.
  7. Monitor the patient closely and provide additional doses every 2 to 3 minutes until they respond or emergency medical assistance becomes available.

What are common precautions when taking Naloxone Nasal Spray?

Some common precautions when taking naloxone nasal spray include:

  1. Asking your doctor about any aspects you don't understand in the patient information leaflet and instructions.
  2. Ensuring that someone close to you is aware of how to handle an emergency situation in case you require assistance to administer the medication.
  3. Keeping the patient under observation and calling for emergency help after administering the initial dose.
  4. Being cautious when using this medicine if you have heart or blood vessel issues, as it could exacerbate these conditions.