How is Rabies Immune Globulin (Intramuscular Route) dosed?
The standard adult dose for post-exposure prophylaxis is 20 units of rabies immune globulin per kilogram of body weight, given intramuscularly. The total dose is usually divided into several injections given on different days, starting as soon as possible after exposure. Additional doses are given on days 3, 7, and 14 after the first dose. Children, pregnant women, and those with bleeding disorders or other medical conditions may require specialized dosing adjustments. It is important to follow the healthcare professional's instructions regarding dosage and timing.
What is the dosage form of Rabies Immune Globulin (Intramuscular Route)?
The dosage form of Rabies Immune Globulin (Intramuscular Route) is a solution.
How is Rabies Immune Globulin (Intramuscular Route) administered?
Rabies immune globulin is administered intramuscularly, typically in the upper arm (deltoid) or thigh muscle. It may also be injected directly into the body part that was bitten or scratched, which caused the exposure to rabies. The injection is given by a healthcare professional in a hospital or clinic setting. It is important to follow the healthcare provider's instructions regarding the administration of this medication.
What are common precautions when taking Rabies Immune Globulin (Intramuscular Route)?
Common precautions when taking Rabies Immune Globulin (Intramuscular Route) include:
- Bleeding disorders or thrombocytopenia (low number of platelets): Use with caution, as it may worsen these conditions.
- Blood clotting problems, heart and blood vessel problems, high cholesterol or fats in the blood, hyperviscosity syndrome (increase in blood consistency), or a requirement for prolonged inactivity: Use with caution, as it may increase the risk of developing thrombosis (blood clots).
- Immunoglobulin A (IgA) deficiencies: Rabies immune globulin may cause an allergic reaction, so use with caution if you have IgA deficiencies.
- Avoid immunizations (vaccinations) without your doctor's approval: Rabies immune globulin may interfere with the effectiveness of some vaccines. Do not receive the measles vaccine within 4 months after receiving rabies immune globulin and avoid other live virus vaccines (e.g., mumps, polio, rubella) within 3 months after receiving this medicine.
- Serious allergic reactions: Rabies immune globulin may cause serious allergic reactions, including anaphylaxis. Seek immediate medical attention if you experience a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving the injection. Please consult your healthcare professional for more information and personalized guidance on taking Rabies Immune Globulin (Intramuscular Route).