Sacubitril and Valsartan

How is Sacubitril and Valsartan dosed?

For heart failure, the recommended dosage is as follows:

  • Adults: Start with 1 tablet of 49 mg of sacubitril and 51 mg of valsartan twice a day. After 2 to 4 weeks, the dose may be increased as needed and tolerated, but it is usually not more than 1 tablet of 97/103 mg twice a day.

What is the dosage form of Sacubitril and Valsartan?

The dosage form of Sacubitril and Valsartan is tablets.

What medications are contraindication with Sacubitril and Valsartan?

Medications that may interact with Sacubitril and Valsartan include:

  1. Angiotensin-converting enzyme (ACE) inhibitors
  2. Angiotensin II receptor blockers (ARBs)
  3. Diuretics (water pills)
  4. Potassium-sparing diuretics
  5. Nonsteroidal anti-inflammatory drugs (NSAIDs)
  6. Certain antibiotics
  7. Antifungal medications
  8. HIV medications
  9. Antiepileptic medications
  10. St. John's Wort It is important to inform your healthcare provider of all medications and supplements you are taking to ensure safe use.

How is Sacubitril and Valsartan administered?

Sacubitril and Valsartan is administered as a tablet. The recommended dosage for patients taking Sacubitril and Valsartan with an ACE inhibitor or ARB is to start with 1 tablet of 49 mg of sacubitril and 51 mg of valsartan, taken twice a day. After 2 to 4 weeks, the dose may be increased as needed and tolerated, but it is usually not more than 1 tablet of 97/103 mg twice a day.

What are common precautions when taking Sacubitril and Valsartan?

Common precautions when taking Sacubitril and Valsartan include:

  1. Allergies
  2. Pediatric use
  3. Geriatric use
  4. Breastfeeding
  5. Drug interactions
  6. Other side effects Always follow your doctor's instructions and read the Medication Guide provided by your pharmacist before starting to use this medicine.