How is Siltuximab dosed?
The recommended dosage for multicentric Castleman's disease (MCD) is 11 mg per kilogram of body weight given as an intravenous infusion over 1 hour. The dosage may vary based on the patient's response to the treatment and any potential side effects. It is essential to follow your doctor's instructions carefully and have regular check-ups to ensure the medicine is working effectively.
What is the dosage form of Siltuximab?
The dosage form of siltuximab is Powder for Solution.
How is Siltuximab administered?
Siltuximab is administered through intravenous (IV) injection only under the direct supervision of a doctor. It is used to treat multicentric Castleman's disease (MCD) in patients without HIV and HHV-8 infection. It is important to follow the instructions provided by your doctor and consult them with any questions. Regular monitoring of progress and potential side effects, including infections, is required. Inform your doctor about any allergies, pregnancy, or plans for pregnancy, as well as any other types of allergies. Caution should be exercised when using this medicine in pediatric and geriatric patients.
What are common precautions when taking Siltuximab?
Common precautions when taking siltuximab include:
- Regular progress monitoring: Your doctor should check your progress at regular visits to ensure the medicine is working effectively. Blood tests may be necessary to check for any unwanted effects.
- Pregnancy and birth control: Inform your doctor if you are pregnant or planning to become pregnant. Effective birth control should be used during treatment and for 3 months after the last dose to prevent pregnancy.
- Infection risk: Siltuximab may reduce your body's ability to fight infections. Notify your doctor at the first sign of infection, such as a fever, chills, cough, flu-like symptoms, or unusual tiredness or weakness.
- Immunizations: Avoid receiving any immunizations (vaccines) without your doctor's approval. Live virus vaccines should not be given with this medicine or shortly after receiving it.
- Infusion reactions: Siltuximab may cause infusion reactions during or after the infusion. Inform your doctor or nurse if you experience back pain, chest pain or discomfort, fast or uneven heartbeat, nausea or vomiting, trouble breathing, or redness of the face, neck, arms, and upper chest.
- Side effects: Inform your healthcare professional if you experience difficulty moving, joint pain, stiffness, or swelling, muscle pain or stiffness, rash with flat lesions or small raised lesions on the skin, darkening of the skin, decreased appetite, dry skin, or skin rash, encrusted, scaly, and oozing. Please note that this information is specific to siltuximab and should not replace discussions with a healthcare professional.