How is Sofosbuvir and Velpatasvir dosed?
The dosage for the oral route of Sofosbuvir and Velpatasvir depends on the strength of the medicine, the patient's weight, and the medical problem being treated. For hepatitis C virus infection:
- Adults: Take one tablet once a day for 12 weeks. Each tablet contains 400 mg of Sofosbuvir and 100 mg of Velpatasvir.
- Children weighing at least 30 kg: The dose is determined by the doctor based on body weight.
- Children weighing 17 to less than 30 kg: Take one tablet (containing 200 mg of Sofosbuvir and 50 mg of Velpatasvir) once a day for 12 weeks.
- Children weighing less than 17 kg: Use oral pellets as recommended.
For oral pellets:
- Children 3 years of age and older or weighing at least 30 kg: The dose is determined by the doctor based on body weight.
What is the dosage form of Sofosbuvir and Velpatasvir?
Sofosbuvir and Velpatasvir are available in the following oral dosage forms:
-
Tablets: The adult dose for hepatitis C virus infection is one tablet containing 400 mg of Sofosbuvir and 100 mg of Velpatasvir, taken once a day for 12 weeks. Dosing for children weighing at least 30 kg is based on body weight and determined by a doctor. For those weighing less than 30 kg, the dose is one tablet (containing 200 mg of Sofosbuvir and 50 mg of Velpatasvir) once a day for 12 weeks.
-
Pellets: Children 3 years of age and older or weighing at least 30 kg are dosed based on body weight and determined by a doctor. For hepatitis C virus infection, they can take two packets containing 200 mg of Sofosbuvir and 50 mg of Velpatasvir, or one packet (containing 150 mg of Sofosbuvir and 37.5 mg of Velpatasvir) once a day for 12 weeks, depending on their weight.
How is Sofosbuvir and Velpatasvir administered?
Sofosbuvir and Velpatasvir are administered through tablets and oral pellets. The dose for adults with hepatitis C virus infection is one tablet (containing 400 mg of Sofosbuvir and 100 mg of Velpatasvir) once a day, taken for 12 weeks. For children weighing at least 30 kg, the dose is based on body weight and must be determined by a doctor. For those weighing 17 to less than 30 kg, the recommended dose is one tablet (containing 200 mg of Sofosbuvir and 50 mg of Velpatasvir) once a day, taken for 12 weeks. Children weighing less than 17 kg are advised to use oral pellets. For children 3 years of age and older weighing less than 17 kg, the dose is determined by a doctor. Children younger than 3 years of age should follow their doctor's instructions for dosing.
What are common precautions when taking Sofosbuvir and Velpatasvir?
Common precautions when taking Sofosbuvir and Velpatasvir include informing your doctor of any allergies you have, particularly to the medicine or any other medicines, foods, dyes, preservatives, or animals. It is also important to follow your doctor's orders or the directions on the label regarding the dosage, frequency, and duration of the medication. In addition, be aware of the potential side effects and notify your healthcare professional if you experience any unusual or severe side effects.