How is Sulfamethoxazole and Trimethoprim Oral Route dosed?
For the treatment of bacterial infections, the recommended dosage for adults is 1 tablet (DS tablet) of 800 mg of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 mL of oral liquid every 12 hours for 10 to 14 days. The dosage for children 2 months of age and older is based on body weight and must be determined by a doctor. It usually consists of 40 mg per kilogram of body weight of sulfamethoxazole and 8 mg per kilogram of body weight of trimethoprim, given in two divided doses every 12 hours for 10 days. For bronchitis, the dosage is the same as for bacterial infections. The dosage for the prevention of Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP) is 800 mg of sulfamethoxazole and 160 mg of trimethoprim once a day for adults. The dosage for children 2 months of age and older is based on body size and must be determined by a doctor.
What is the dosage form of Sulfamethoxazole and Trimethoprim Oral Route?
The oral dosage forms of sulfamethoxazole and trimethoprim are liquid or tablets.
How is Sulfamethoxazole and Trimethoprim Oral Route administered?
For oral dosage forms (liquid or tablets) of sulfamethoxazole and trimethoprim, the administration depends on the age, body weight, and condition being treated. The dosage is determined by your doctor based on body weight, and it is typically given in two divided doses every 12 hours for the specified duration. For treatment of traveler's diarrhea, the usual duration is 5 days. It is essential to follow the dosage instructions provided by your doctor and not exceed the recommended dosage.
What are common precautions when taking Sulfamethoxazole and Trimethoprim Oral Route?
Common precautions when taking sulfamethoxazole and trimethoprim oral route include:
- Enzyme problems: Use with caution for those with enzyme problems like Glucose-6-phosphate dehydrogenase (G6PD) deficiency, as it may cause hemolytic anemia.
- Specific infections: Do not use in patients with streptococcal infection or severe allergies.
- Thyroid problems and porphyria: These conditions may worsen when using sulfamethoxazole and trimethoprim.
- Dosage adjustments: The dose may need to be adjusted for elderly patients.
- Pediatric use: Generally safe for children 2 months of age and older, but not recommended for infants younger than 2 months.
- Pregnancy and breastfeeding: Consult your doctor before using sulfamethoxazole and trimethoprim if you are pregnant, breastfeeding, or planning to become pregnant. It is important to follow the dosage instructions provided by your doctor and drink extra water to prevent unwanted side effects. If you experience any side effects or concerns, consult your healthcare professional.