Sulfasalazine oral route

How is Sulfasalazine oral route dosed?

For the treatment of ulcerative colitis in pediatric patients aged 2 years and older, the recommended initial dose is 50 to 100 mg every 6 hours, with a maximum daily dose of 2.0 g. The dose may be gradually increased by 50 mg every 6 hours until a maximum daily dose of 2.0 g is reached or until a satisfactory response is achieved.

For the treatment of juvenile rheumatoid arthritis in pediatric patients aged 6 years and older, the initial dose is 500 mg per day in divided doses, and the dose may be gradually increased by 500 mg every 6 weeks until a maximum daily dose of 2.5 to 3.0 g is reached or until a satisfactory response is achieved.

For geriatric patients, the dosage should be adjusted based on the patient's age, condition, and other medications they are taking.

It is important to follow the dosing instructions provided by your doctor or the label carefully. If you have any questions or concerns about the dosing of sulfasalazine oral route, consult your healthcare professional.

What is the dosage form of Sulfasalazine oral route?

The dosage forms of sulfasalazine oral route are tablets and enteric-coated tablets.

What medications are contraindication with Sulfasalazine oral route?

Sulfasalazine oral route should not be used if you have an allergy to sulfa drugs or salicylates, blood or bone marrow problems (e.g., agranulocytosis, aplastic anemia), heart disease, kidney disease, liver disease, or lung or breathing problems (e.g., bronchial asthma). It is essential to discuss any other medications or medical conditions with your healthcare professional before using sulfasalazine to ensure safe usage.

How is Sulfasalazine oral route administered?

Sulfasalazine oral route is administered by swallowing the enteric-coated tablet whole, without crushing, breaking, or chewing it. It is important to drink extra fluids while taking this medication to help prevent kidney problems. The dosage and duration of treatment should be as directed by a healthcare professional and as specified on the label, and patients should not miss any doses.

What are common precautions when taking Sulfasalazine oral route?

When taking sulfasalazine orally, the following common precautions should be observed:

1. Blood Problems: Sulfasalazine may cause blood problems, which could result in an increased risk of infections, slow healing, and bleeding of the gums. Be cautious when using regular toothbrushes, dental floss, and toothpicks. Postpone dental work until your blood counts have returned to normal. Consult your doctor or dentist for advice on proper oral hygiene during treatment.

2. Sun Sensitivity: Sulfasalazine may make your skin more sensitive to sunlight. Avoid direct sun exposure, especially between 10:00 a.m. and 3:00 p.m. Wear protective clothing, including a hat and sunglasses, to prevent skin reactions such as rash, itching, redness, or discoloration.

3. Age-related Use: Safety and efficacy of sulfasalazine have not been established in children under 2 years old for treating ulcerative colitis. For juvenile rheumatoid arthritis, sulfasalazine enteric-coated tablets have been deemed safe and effective, but safety and efficacy have not been established for children under 6 years old.

4. Geriatric Use: Sulfasalazine can be used in elderly patients, but dosage adjustments may be necessary based on age, condition, and other medications being taken.

5. Breastfeeding: If you are breastfeeding and taking sulfasalazine, monitor the infant for side effects and adequate milk intake, as it may affect milk production or composition.