Tazemetostat

How is Tazemetostat dosed?

The recommended oral dosage for tazemetostat is 800 mg, taken twice a day. The dosage may be adjusted by the doctor as needed.

What is the dosage form of Tazemetostat?

Tazemetostat is available in tablet form.

What medications are contraindication with Tazemetostat?

Tazemetostat should not be used with the following medications due to potential interactions: Phenobarbital, Phenytoin, Posaconazole, Primidone, Rifabutin, Rifampin, Ritonavir, Saquinavir, Segesterone, St. John's Wort, Telaprevir, Telithromycin, Ulipristal, Verapamil, and Voriconazole. Inform your doctor about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, to avoid potential interactions with tazemetostat.

How is Tazemetostat administered?

Tazemetostat is administered as a tablet. The recommended dosages for adults and children 16 years of age and older with epithelioid sarcoma are 800 milligrams (mg) taken twice a day. For follicular lymphoma, the dosage for adults is also 800 mg taken twice a day. Children's dosages must be determined by their doctor. Follow the instructions of your healthcare professional and always take the medicine as prescribed.

What are common precautions when taking Tazemetostat?

Common precautions when taking tazemetostat include:

  1. Consult your doctor: Inform your doctor about any medical conditions, allergies, or medications you are currently taking before starting tazemetostat. Follow your doctor's instructions and seek medical advice for any side effects or concerns.
  2. Monitor for side effects: Tazemetostat may cause side effects such as nausea, fatigue, diarrhea, and changes in blood cell counts. Contact your doctor if you experience severe side effects or if they persist.
  3. Pregnancy and breastfeeding: Consult your doctor before using tazemetostat if you are pregnant, planning to become pregnant, or breastfeeding. The safety and efficacy of this medication have not been established in pregnant or breastfeeding women.
  4. Geriatric considerations: The safety and efficacy of tazemetostat have not been established in the geriatric population. Elderly patients may be more sensitive to the side effects of this medication.
  5. Pediatric use: The safety and efficacy of tazemetostat have not been established in children younger than 16 years of age with epithelioid sarcoma and in children with follicular lymphoma. Use and dosage must be determined by your doctor.
  6. Drug interactions: Inform your doctor about all the medications, herbal supplements, and vitamins you are taking to avoid potential drug interactions with tazemetostat.
  7. Follow dosing instructions: Take tazemetostat exactly as prescribed by your doctor. Do not adjust your dose or stop taking the medication without consulting your doctor.
  8. Storage: Store tazemetostat at room temperature, away from moisture and light. Keep the medication out of reach of children and dispose of any outdated or unused medicine as directed by your healthcare professional. Always follow your doctor's instructions and consult them if you have any questions or concerns about taking tazemetostat.