How is Telaprevir dosed?
Telaprevir should be taken with food containing about 20 grams of fat, within 30 minutes after eating a high-fat meal or snack. Please consult with a healthcare professional for specific dosing instructions.
What is the dosage form of Telaprevir?
Telaprevir is available in tablet form. The dosage for adults with hepatitis C virus infection, when used in combination with peginterferon alfa and ribavirin, is 750 mg (two 375-mg tablets) taken three times a day with food, with each dose taken 7 to 9 hours apart. Children's dosages are determined by their doctor.
What medications are contraindication with Telaprevir?
Telaprevir should not be used with alfuzosin (Uroxatral), cisapride (Propulsid), oral midazolam (Versed), pimozide (Orap), rifampin (Rifadin, Rimactane), sildenafil (Revatio), St. John's wort, tadalafil (Adcirca), triazolam (Halcion), and certain cholesterol-lowering medicines (such as lovastatin, simvastatin, Mevacor, Zocor), or ergot medicines (such as dihydroergotamine, ergonovine, ergotamine, methylergonovine, Cafergot, Ergomar, Wigraine). Using telaprevir with any of these medicines can cause very serious medical problems.
How is Telaprevir administered?
Telaprevir should be taken within 30 minutes after eating a high-fat meal or snack containing about 20 grams of fat. It should be used on a regular schedule and combined with peginterferon alfa and ribavirin for the full duration of treatment, even if the patient starts to feel better after a few days. It is important to follow the dosing instructions provided by a doctor and read the Medication Guide carefully.
What are common precautions when taking Telaprevir?
Here are some common precautions when taking telaprevir:
- Be cautious if you have a weakened immune system, liver disease, or any other medical conditions, as telaprevir may worsen these conditions.
- Avoid using telaprevir with specific medications, such as alfuzosin, cisapride, oral midazolam, pimozide, rifampin, sildenafil, St. John's wort, tadalafil, triazolam, certain cholesterol-lowering medicines, or ergot medicines, as they can cause severe medical problems when combined with telaprevir.
- Inform your doctor if you experience severe skin reactions, such as rash, blistering, peeling, or loosening of the skin, fever or chills, hives or welts, red skin lesions, acne, sores or ulcers on the skin, or yellowing of the skin or the whites of your eyes.
- Take telaprevir within 30 minutes after eating a high-fat meal or snack containing about 20 grams of fat to help keep the amount of medicine in your body at a steady level.
- Follow the instructions in the Medication Guide provided by your doctor or pharmacist carefully. Remember to consult your doctor before taking telaprevir, especially if you have any allergies, are pregnant or breastfeeding, or have any concerns about your medical conditions.