How is Tipranavir oral route dosed?
For adults, the typical dose is 500 milligrams (two capsules or 5 milliliters) of tipranavir and 200 milligrams of ritonavir (Norvir) taken twice a day. Children's dosages are based on body weight or body size, determined by a doctor, and typically range between 14 to 375 milligrams per kilogram of tipranavir plus 6 to 150 milligrams per kilogram of ritonavir (Norvir) taken twice a day. The dose should not exceed the recommended adult dose.
What is the dosage form of Tipranavir oral route?
The dosage forms of tipranavir oral route include capsules and oral solution. For treatment of HIV infection, the recommended oral dosage for adults is 500 milligrams (mg) (two capsules or 5 milliliters (mL)) of tipranavir and 200 mg of ritonavir (Norvir) two times a day. The dose for children 2 to 18 years of age is based on body weight or body size, usually 14 milligrams (mg) per kilogram (kg) of body weight of tipranavir plus 6 mg per kg of body weight of ritonavir (Norvir), or 375 mg/m^2 of body size of tipranavir plus 150 mg/m^2 of body size of ritonavir two times a day.
What medications are contraindication with Tipranavir oral route?
Tipranavir oral route should not be used with the following medications due to potential serious medical problems: alfuzosin (Uroxatra), amiodarone (Cordarone, Pacenone), bepridil (Vascor), cisapride (Propulsid), ergot medicines (eg, dihydroergotamine, ergonovine, ergotamine, methylergonovine, Cafergot, Methergine, Migrana), flecainide (Tambocor), lovastatin (Altocor, Mevacor), oral lurasidone (Latuda), midazolam (Versed), pimozide (Orap), propafenone (Rythmo), quinidine (Cardioquin, Quinaglute Dura), rifampin (Rifadin, Rimactane), sildenafil (Revatio), simvastatin (Simcor, Vytorin, Zocor), or triazolam (Halcion).
How is Tipranavir oral route administered?
Tipranavir oral route can be administered as either capsules or oral solution. The recommended adult dose for treatment of HIV infection is 500 milligrams (mg) (two capsules or 5 milliliters (mL)) of tipranavir and 200 mg of ritonavir (Norvir) two times a day. For children 2 to 18 years of age, the dose is determined based on body weight or body size and typically ranges from 14 milligrams (mg) per kilogram (kg) of body weight of tipranavir plus 6 mg per kg of body weight of ritonavir (Norvir), or 375 mg/m^2 of body size of tipranavir plus 150 mg/m^2 of body size of ritonavir two times a day. It is important to follow the dosage instructions provided by your doctor and read the patient information insert carefully.
What are common precautions when taking Tipranavir oral route?
Common precautions when taking tipranavir oral route include:
- Always taking it with ritonavir (Norvir).
- Taking the medicines at the same time, unless advised otherwise by your doctor.
- Following the dosing instructions carefully, which may vary depending on whether you are using ritonavir capsules or tablets.
- Swallowing the capsule whole and not breaking, crushing, or chewing it.
- Measuring the oral liquid with a marked measuring spoon, oral syringe, or medicine cup, as the average household teaspoon may not hold the right amount of liquid. Please consult your healthcare professional for specific guidance and any additional precautions based on your medical history and current health conditions.