Upadacitinib

How is Upadacitinib dosed?

The recommended dosage of Upadacitinib varies based on the condition being treated. For rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, Crohn's disease, and atopic dermatitis, the recommended dosage is 15 mg, taken once daily. However, it is essential to follow your doctor's prescription, as the dosage may be adjusted based on individual factors and response to treatment.

What is the dosage form of Upadacitinib?

The dosage form of Upadacitinib is a tablet, extended release.

What medications are contraindication with Upadacitinib?

It is essential to inform your doctor about all medications you are currently taking, including prescription, over-the-counter, and herbal products, as they might interact with Upadacitinib. Additionally, you should follow your doctor's advice regarding any medication interactions or contraindications based on your medical history and individual health conditions.

How is Upadacitinib administered?

Upadacitinib is administered as a tablet, extended release. It should be taken exactly as directed by your doctor, neither more nor less, and not for a longer time than prescribed. The extended-release tablets should be swallowed whole with water, not cut, crushed, broken, or chewed. Always follow the Medication Guide provided and consult your doctor if you have any questions.

What are common precautions when taking Upadacitinib?

Here are common precautions to keep in mind when taking Upadacitinib:

  1. Sun Sensitivity: Upadacitinib may make your skin more sensitive to sunlight. Use a sunscreen and avoid sunlamps and tanning beds.
  2. Immunizations: Do not have any immunizations (vaccines) without your doctor's approval while taking Upadacitinib and after you stop treatment. Upadacitinib may lower your body's resistance, increasing the risk of infections from vaccines.
  3. Cholesterol and Fat Levels: This medicine may increase the level of cholesterol and fat in your blood. Discuss any concerns with your doctor.
  4. Age-related Considerations: Appropriate studies have not been performed on the relationship of age to the effects of Upadacitinib in children and the elderly. Elderly patients may be more likely to experience serious infections and cancer while taking Upadacitinib.
  5. Breastfeeding: There is limited information on the safety of Upadacitinib use during breastfeeding. Consult your doctor to weigh the potential benefits and risks.
  6. Tuberculosis Skin Test: You will need to have a skin test for tuberculosis before starting Upadacitinib. Inform your doctor if you or someone in your home has had a positive reaction to a tuberculosis skin test.
  7. Infections: Your body's ability to fight infections may be reduced while taking Upadacitinib. Contact your doctor at the first sign of an infection, such as fever, chills, cough, flu-like symptoms, or unusual tiredness or weakness.
  8. Heart or Blood Vessel Problems: Upadacitinib may increase the risk of serious heart or blood vessel problems, especially in rheumatoid arthritis patients over 50 years of age and with a heart or blood vessel disease. Seek medical attention if you experience symptoms like chest pain or discomfort, confusion, difficulty speaking, double vision, headache, inability to move arms, legs, or facial muscles, nausea, pain in the arms, jaw, back, or neck, sweating