How is Ustekinumab Injection dosed?
The dosage of ustekinumab injection depends on the medical condition being treated, patient's weight, and doctor's orders. For Crohn's disease and ulcerative colitis:
- Adults weighing more than 85 kilograms (kg): 520 milligrams (mg) (4 vials) injected into your vein as a single dose.
- Adults weighing more than 55 kg to 85 kg: 390 mg (3 vials) injected into your vein as a single dose. Please follow your doctor's orders or the instructions on the label for the appropriate dosage.
What is the dosage form of Ustekinumab Injection?
Ustekinumab injection is available in the form of a prefilled syringe. It is used to treat moderate to severe plaque psoriasis, active psoriatic arthritis, moderate to severely active Crohn's disease, and ulcerative colitis. The dose is determined by the patient's weight and medical condition, and it is administered by a healthcare professional through a vein or as a subcutaneous injection.
What medications are contraindication with Ustekinumab Injection?
Medications that may interact with ustekinumab injection and could lead to contraindications include:
- Live vaccines: The use of live vaccines such as rotavirus, rubella, smallpox, typhoid, varicella, yellow fever, and zoster vaccines should be avoided while using ustekinumab injection.
- Tuberculosis (TB) medications: Using ustekinumab injection with TB medications may increase the risk of serious infections. Ensure that any TB infection is treated before starting therapy with ustekinumab injection.
- Other immunosuppressant medications: Combining ustekinumab injection with other immunosuppressant medications may increase the risk of infections, cancer, and other side effects. Examples include other biologic medications, corticosteroids, and immunomodulatory drugs. It is essential to discuss with your healthcare professional all medications, supplements, and herbal products you are currently taking, as well as any medical conditions, to ensure safe use of ustekinumab injection.
How is Ustekinumab Injection administered?
Ustekinumab injection can be administered through a needle placed into one of your veins or as a shot under your skin. The injection sites are usually on the upper arms, buttocks, stomach, or thighs. It may sometimes be given at home to patients who do not need to be in the hospital or clinic, with proper training from a healthcare professional.