Kidney Transplant

An overview of Kidney Transplant

A kidney transplant evaluation is a comprehensive process to determine if a person is eligible for a kidney transplant. This evaluation is carried out by a transplant center team and includes various tests and assessments to ensure that the candidate is in good health, has a willingness to follow post-transplant medication regimens, and does not have any medical conditions that could interfere with the success of the transplant. The evaluation process typically takes several days and involves a thorough physical exam, imaging studies such as X-ray, MRI or CT scans, blood tests, and a psychological evaluation. The goal of this evaluation is to determine whether a candidate is suitable for a kidney transplant and to match them with a suitable donor kidney.

What is Kidney Transplant used for?

A kidney transplant is a surgical procedure used to replace a diseased or nonfunctional kidney with a healthy kidney from a living or deceased donor. This is typically done to treat chronic kidney disease or end-stage renal disease, which occur when the kidneys have lost a significant portion of their function. The primary goal of a kidney transplant is to improve the quality of life and extend the lifespan of the recipient. Compared to dialysis, a transplant can offer better outcomes, including a higher quality of life, lower risk of death, fewer dietary restrictions, and lower treatment costs. However, not everyone is eligible for a kidney transplant, as certain medical conditions or lifestyle factors may increase the risk of complications during or after the surgery.

How to prepare for Kidney Transplant?

Before a kidney transplant evaluation, there are several preparations that patients need to make:

  1. Choose a transplant center: Research and select a transplant center that meets your needs and preferences. This will be where you'll undergo the evaluation process.
  2. Consult with your primary care physician: Discuss your interest in a kidney transplant with your primary care physician. They can provide a referral to a transplant center if necessary.
  3. Gather medical records: Collect any relevant medical records, test results, and reports related to your kidney disease or current health condition. This information will be useful during the evaluation process.
  4. Prepare for the evaluation process: The evaluation process typically includes a thorough physical exam, imaging studies, blood tests, and a psychological evaluation. Ensure you have fasted for the required period before blood tests and are prepared for any other necessary testing.
  5. Be prepared to share your medical history: Be ready to discuss your medical history, current health status, and any medications you are taking with the transplant team.
  6. Be open to lifestyle changes: As a kidney transplant candidate, you may need to make lifestyle changes to improve your overall health before the transplant. This could include quitting smoking, adopting a healthier diet, and regular exercise.
  7. Inform your transplant team of any changes: If there are any significant changes in your health, inform your transplant team immediately. This includes changes in your medication regimen, new symptoms, or any other relevant information.

Remember to follow your transplant team's instructions and stay in close communication with them throughout the evaluation process.

How is Kidney Transplant conducted?

Kidney transplant tests involve a series of evaluations to determine whether a donor kidney will be a good match for the recipient. The tests include blood typing, tissue typing using human leukocyte antigen (HLA) typing, and a crossmatch. Blood typing checks the compatibility of blood types between the donor and recipient. Tissue typing, or HLA typing, assesses genetic markers to predict the likelihood of transplant success and long-term kidney function. Finally, a crossmatch tests for potential antibody reactions between the recipient's and donor's blood, ensuring compatibility and reducing the risk of organ rejection. These tests help the transplant team find the most suitable donor kidney for the recipient.

How are Kidney Transplant results reported?

Kidney transplant success rates are typically reported through survival rates among transplant recipients in U.S. transplant centers. These rates can be found online at the Scientific Registry of Transplant Recipients website.

Understanding the report

After going through the evaluation process at a transplant center, the results are used to determine whether the individual meets the center's eligibility requirements for a kidney transplant. The transplant team assesses the candidate's overall health, their ability to tolerate post-transplant medications, and whether they have any medical conditions that may interfere with transplant success. They also evaluate the candidate's willingness and ability to adhere to the prescribed medications and follow the transplant team's suggestions.

The results of the evaluation process may take several days to be completed. The thorough physical exam, imaging studies such as X-ray, MRI or CT scans, blood tests, and psychological evaluation are all components of this process. The transplant team will discuss the results with the candidate and inform them whether they have been accepted as a kidney transplant candidate. It's important to note that each transplant center has its own eligibility criteria, so if a candidate is not accepted at one center, they may apply to others.

Once a suitable kidney donor has been found, the compatibility of the donor kidney with the recipient is assessed through blood typing, cross-matching, and other tests. The success of the transplant depends on various factors, including the health of the donor kidney, the recipient's overall health, and post-transplant care and management.

Post-transplant, the recipient will need to take immunosuppressant medications to prevent rejection of the new kidney and undergo regular checkups to monitor their health and the functioning of the transplanted kidney. It's important for transplant recipients to adhere to their medication regimen, attend follow-up appointments, and maintain a healthy lifestyle to ensure the long-term success of the transplant.