Overview
Gilbert's Syndrome is a common, mild liver disorder where the liver does not properly metabolize a waste product called bilirubin. This results in high levels of bilirubin in the blood, causing the skin and whites of the eyes to appear yellowish (jaundice). However, Gilbert's Syndrome does not impair liver function, and most people with this condition do not experience any symptoms. The yellowing of the skin and eyes typically occurs after exposure to stress, illness, or certain medications, and it resolves on its own within a few days to weeks. Gilbert's Syndrome is genetic and cannot be cured, but it usually does not require treatment unless symptoms become severe or affect quality of life.
Understanding the disease
Development
Gilbert syndrome is an inherited genetic condition. It is caused by a modified gene that controls an enzyme involved in breaking down bilirubin in the liver. People with Gilbert syndrome have an ineffective gene that results in insufficient production of the enzyme, leading to higher bilirubin levels in the blood. The condition typically does not cause any symptoms or require treatment, but it may cause a yellowish tinge to the skin and whites of the eyes during times of increased bilirubin production, such as during illness, fasting, dehydration, menstruation, strenuous exercise, or stress.
Assessment and Diagnosis
Diagnosis
To diagnose Gilbert syndrome, your health care provider may suspect it based on your symptoms, which can include unexplained jaundice, dark urine, and abdominal pain. They may also order a complete blood count and liver function tests to rule out other liver conditions. An elevated bilirubin level in your blood, in combination with standard blood counts and liver enzymes, can indicate Gilbert syndrome. Genetic testing can also be done to confirm the diagnosis. There is no specific treatment required for Gilbert syndrome, as the bilirubin levels may fluctuate over time, and jaundice usually resolves on its own with no ill effects. Managing life events that may trigger episodes of higher bilirubin levels can help keep the condition under control.
Management and Treatment
Home Remedies
There are no specific home remedies suggested for Gilbert's syndrome as it is a genetic condition that doesn't require treatment. However, some general home remedies can help manage symptoms such as maintaining a balanced diet, staying hydrated, and avoiding fasting or low-calorie diets. It's essential to consult with a healthcare provider for personalized advice and guidance.
Treatment
There is no specific treatment for Gilbert syndrome. The condition is managed through lifestyle modifications and self-care measures. The main focus is on maintaining a healthy diet, avoiding extreme calorie restrictions, managing stress, and ensuring that healthcare providers are aware of the condition. Gilbert syndrome is a genetic disorder that affects the body's ability to process bilirubin, leading to episodes of jaundice. While the bilirubin levels may fluctuate over time, there is no need for medical intervention. However, managing stress and maintaining a routine eating schedule can help keep bilirubin levels under control.