Overview
Sclerosing mesenteritis is a rare and progressive inflammatory condition that affects the mesentery, the membrane that attaches the intestine to the abdominal wall. It is characterized by thickening and hardening of the mesentery, which can lead to bowel obstruction, reduced blood flow, and damage to the intestinal tissue. The exact cause of sclerosing mesenteritis is unknown, but it is believed to be an autoimmune disorder or a reaction to a bacterial or viral infection. The symptoms may include abdominal pain, bloating, weight loss, diarrhea, constipation, and malabsorption of nutrients. Treatment options may include surgery, immunosuppressive medications, and bowel rest.
Understanding the disease
Assessment and Diagnosis
Diagnosis
To diagnose sclerosing mesenteritis, your doctor will typically perform a physical exam, where they will look for clues that may help determine the diagnosis. Sclerosing mesenteritis often forms a mass in the upper abdomen that can be felt during a physical exam. Imaging tests, such as computerized tomography (CT) or magnetic resonance imaging (MRI), may also be used to reveal the presence of sclerosing mesenteritis. In some cases, a biopsy may be recommended to rule out other diseases and make a definitive diagnosis. A biopsy sample can be collected by inserting a long needle through the skin or during surgery.
Management and Treatment
Treatment
Treatment for sclerosing mesenteritis typically involves controlling inflammation through medications. The main medications used for sclerosing mesenteritis are corticosteroids, which help control inflammation. These medications are usually used for a period of three to four months due to potential side effects. In addition, hormone therapy with tamoxifen or progesterone may be used to slow the growth of scar tissue. Other drugs, such as azathioprine, colchicine, cyclophosphamide, and thalidomide, have also been used to treat sclerosing mesenteritis. If the condition advances and blocks the flow of food through the digestive system, surgery may be necessary to remove the blockage. It's important to consult with a medical professional for personalized treatment recommendations.
Preparing for medical consultation
Here's how to prepare for an appointment for sclerosing mesenteritis:
- Pre-appointment restrictions: At the time you make your appointment, ask if there are any restrictions you need to follow in the time leading up to your visit, including whether you should be isolated to avoid spreading the infection.
- Symptom history: Write down any symptoms you've been experiencing, and for how long, including abdominal pain, bloating, diarrhea, and weight loss.
- Recent exposure to possible sources of infection: Inform your doctor about any recent travel, contact with animals, or exposure to contaminated food.
- Medical history: Make a list of your key medical information, including other health conditions, current medications, and any recent hospitalizations or surgeries.
- Vaccination record: Find out before your appointment whether your vaccinations are up to date. Bring a copy of your vaccination record, if possible.
- Medications: Bring all of your medications with you, preferably in their original bottles.
- Take a family member or friend: Sclerosing mesenteritis can be a serious condition, so it's a good idea to have someone with you who can understand and recall the information provided by your doctor and stay with you if needed.
- Write down questions to ask your doctor: Prepare a list of questions to ask your healthcare provider, such as the types of tests needed, recommended treatments, potential long-term complications, and precautions to take to avoid spreading the infection. Remember to follow any pre-appointment instructions provided by your doctor, and be prepared to discuss your symptoms, medical history, and any concerns you may have.